In 2012, we founded the Pediatric Neuro-Oncology Consortium (PNOC) driven by the unacceptable reality that children with brain cancer were facing bleak prospects. We embarked on a mission to change the narrative. With a vision that was bold, innovative, and collaborative, we aimed to challenge the status quo and bring hope where there was none. PNOC has not only flourished but has become a beacon of hope and a global leader in the fight against pediatric brain cancer. Through the dedication of nearly 300 researchers across more than 40 institutions worldwide, we have launched groundbreaking clinical trials, offering new treatments tailored to the unique biology of each child's tumor. This patient-centric approach has provided new options for those who previously had none. It has given families precious time together.

Our ability to bypass bureaucratic hurdles and rapidly translate innovative ideas into actionable trials has been nothing short of revolutionary. By leveraging private philanthropy and making collaboration a cornerstone of our work, we've achieved unprecedented speed and flexibility in our research efforts, proving that the only way forward is together – no one researcher or institution will solve this problem alone. We know our work has just begun. We are proud of the progress we’ve made but know there is no victory without a cure. With more families facing these awful diseases each day, our resolve to push the boundaries of what is possible in pediatric neuro-oncology research has only strengthened. We are committed to expanding our global reach, enhancing our research capabilities, and ultimately, ensuring that no child is lost to brain cancer.

We extend our deepest thanks to you, our community of supporters, for believing in our vision and joining our cause. Together, we have built a strong platform, but the road ahead is long and requires our collective effort, innovation, and compassion. We invite you to continue this journey with us, to dream bigger, and to help us bring about a future where every child facing brain cancer has a fighting chance.

Dr. Sabine Mueller and Dr. Mike Prados

Pediatric Neuro-Oncology Consortium (PNOC) Co-founders